Mnemosyne features

The Mnemosyne family of integrated Single-Use-Pump's consist of two parts:

The re-usable pump non-wetted body containing sensors, electronics, pneumatic controlled pinch valves, communication and 1, 2 or 4 diaphragm (cardiac muscle)
The single-use, disposable wetted parts consisting of a dome housing (Thorax) to which both the elastic membrane (Pericardium) and the fluid conveying hoses are attached and supplied pre-sterilized in dual film bags.

Integrated products, model names	Calliope	Erato	Thalia	Polyhymnia
Cabinet	Hephaestus U2	Hephaestus U2	Stand-alone	Stand-alone
Layout, number of diaphragms	dual	single	dual	quadruple
Diaphragm diameter, mm	40	100	150	100
Stroke Volume, SV, mL/stroke	2 x 0 - 25	1 x 0 - 150	2 x 0 - 400	4 x 0 - 150
Pump capacity, CO range, mL/min	2 x 0 - 600	1 x 0 - 3.000	2 x 0 - 6.000	4 x 0 - 3.000
Hose connection, ID/OD mm	3/6	6-8/10-12	8-10/12-15	12/18

CO = Cardiac Output = (CO = BpM x SV), CO variation = >1:1.000

No expensive housing materials for traditional steam cleaning requirements
No mechanical or liquid axle seals, no rotating parts such as electrical motor, coupling or gearboxes
No ball valves, but controlled pinch valves which do not requiring cleaning
No pumped media contact to pump body parts – contamination not possible
Low weight and compact design gives OEM manufactures freedom to design equipment
Able to pump controlled volumes of any fluid, liquid independent of reasonable inlet and outlet pressure
Measures accurately the pumped volume, no in-line flow-sensor is needed
No need for calibration
All pumps offer infinite turn-down, turn-up scale

Two or more independent pumps able to operate fully controlled in parallel
Working pressure as much as 5 Bar makes the pump suitable for connection with filtration devices
Very gentle operation with no rotating parts
Polyhymnia integrate 4 diaphragm SUPs able to operate combined or independent and hereby useful for concentrate mixing of 4 different fluids with just one pump
Use 3^rd and/or 4^th active membranes in Polyhymnia as pulse damper or obtain even higher fluid transfer
Single-use, low-cost, disposable wetted parts eliminate cleaning issues – just un-pack and exchange
Self-emptying, drain on inlet and purge on outlet and the pump will convey gas as well
Self-priming and able to run dry for extended periods
Zero spallation / shedding of materials as no shear is introduced between the used polymeric materials
NO silicone nano particles introduced into the fluid stream like from peristaltic pumps
Max volume per stroke depending on pump size, no minimum volume exist

Choose one pulse/stroke per day or one pulse per second or any set of pulses in between
Choose any stroke length and any fraction of a pulse again and again
Any imaginable operation sequence, cycle for each diaphragm (pulse ramp, pulse train, pulse length, pulse pause, stroke start, stroke length, stroke distance)
Choose the fluid pressure you want to create – 5 - 6 Bar (depending on supply air pressure)
Choose the volume you want to pump – (well, according to pump size)
Real-time information about pumped volume from each diaphragm
Data acquisition, data logging for each diaphragm

No lubrication needed
No need for strip down pump for cleaning
Controlled pinch valves - not part of single-use SUP assembly (wetted parts)
Longevity – diaphragm tested to last +6 month at full stroke length and pulse speed

Single-Use-Pump parts may be part of an all sterile process package with hoses, connectors, etc.
No tooling needed for SUP cell part replacement – well, a scissor to open the bag!
Stainless Steel quick release couplings offer easy access for wetted SUP cell replacement - simple "bolt-on"

On-line pressure sensing from build-in sensor
On-line fluid measurement, metering, the pump measures the volume pumped accurately without external mass flow sensors